Would it be profitable? Yes. Almost anything you do except for folding will be profitable when you have a full house.
Would it be maximally profitable? No. When you have a full house, you block a lot of your opponents' continuing range, so unless there is something to indicate your opponent has a hand strong enough to call, you will usually profit more with a smaller bet size. Also, your opponents don't have to be geniuses to eventually notice if every time you make a massive overbet, you have a monster. Which means that perceptive opponents will have an easy fold, unless you start balancing your all-ins with some bluffs. But it gets worse. Good opponents will also eventually discover that when you don't bet all-in, you can't have a full house, which they can use to exploit you when the board pairs.