Whoo 7 years late, but i saw this question pop up and i thought it was an interesting one.
I think there's a general flaw in the way the hand is thought through by the other answers. Before you think about whether a hand is good to bluff, you should consider what your value range is. I disagree that you will never have a queen here, and if people are suggesting that any ace will snap your bet, it is a losing strategy because you can easily pot it with a queen.
To V's hand, the big bets PF and flop suggest to me that V is on a vulnerable hand (AK, AJ) or on a bluff. There are a ton of bad turns for these hands that lose them the pot or kill action, so IMO sets (AA,QQ,33) are going to be less likely. Anything like a weak A or Q (KQ, QJ) is possibly going to check back for pot control.
The turn is a Q. You should have some Qs in your range (KQ, QJ,... QT?) that called flop and lead out, as it is possible V checks back an Ace here. You will also have some bluffs (e.g. KJs, KTs, KJs) for the flush + straight draw that probably cannot call a turn barrel on a paired board. Opponent calls a hefty bet on the turn, which he is unlikely to do with a draw, so I'll put him on an Ace mostly, and sometimes a Q.
River is a bad card for your opponent because they are going to be mostly Ace pair on this board, while you have many more Qs, and some flushes. On this board i think you can easily valuebet all your Qs, and KJs, KTs, JTs, folding the flushes to a reraise. Thats 19 value combos. I highly doubt its +EV for V to call with any ace.
If your turn bet was for 16 combos of value (KQ, QJ), and 12 combos of bluffs (any KJ, KT, JT with at least one spade), this is reasonably balanced. By the river this range is 19 combos of value and 9 combos of bluffs. Even if you bet all your bluffs here its likely profitable with a 60-70% pot river bet.
Again, this is dependent on whether you would take this line with a Q, which i think is definitely possible, especially against a less aggressive opponent that may check the turn.