Kind of disagree with @raymond so i'll add my own answer.
When everyone plays really loose, i find that loosening up is quite profitable (but still tighter than the rest). IE if my opening range is about 20%, but half the table is playing 80% of hands, then ill start to open up wider (maybe 35%). This gives me an opportunity to play more hands with a stronger range, and i would need to worry less about dominated hands like KJ, AT, etc.
KQs to me is definitely premium enough in position to start building a pot. You're not really here to steal blinds, you want a reasonable pot you can outplay and take down postflop. Hence i'd be raising somewhere between 7-9BB. You want to put hands that limp in tough positions, and you want junk hands to call. A hand like J9o or A7o can easily call the 4x, and easily fold the 15x.
Against multiple callers its likely profitable to never bluff. Most of the time if you hit a pair it would be top pair, and you should hit it enough to be +EV multiway. Headsup you may need to consider how your opponent tends to play, his aggression etc, before considering how to proceed.